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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 

Question 4: Short-term Objective B

green dot 4SB. Standardize and validate at least 20 model systems (e.g., cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012. IACC Recommended Budget: $75,000,000 over 5 years.

Projects Found: 94
Total Funding: 21232514
Records
Project Title Funding Funding Institution

Project Title

Using induced-pluripotent stem cells to study Phelan McDermid Syndrome
$40,000

Funding

40000

Institution

Stanford University School of Medicine

Project Title

Role of astrocytic glutamate transporter GLT1 in fragile X
$40,000

Funding

40000

Institution

Tufts University

Project Title

Evaluating hyperserotonemia as a biomarker of sensory dysfunction in autism spectrum disorder
$28,600

Funding

28600

Institution

Vanderbilt University

Project Title

Temporally controlled genetic rescue of Shank3 autism model
$60,000

Funding

60000

Institution

University of Texas Southwestern Medical Center

Project Title

Integrative system biology of iPSC-induced neurons for identifying novel drug targets
$55,200

Funding

55200

Institution

Baylor College of Medicine

Project Title

Preclinical therapeutic target validation of glutamate receptors in Shank3 models of autism
$56,900

Funding

56900

Institution

University of Texas Southwestern Medical Center

Project Title

Novel approaches to enhance social cognition by stimulating central oxytocin release
$149,852

Funding

149852

Institution

Emory University

Project Title

Rat knockout models of ASD
$100,441

Funding

100441

Institution

Baylor College of Medicine

Project Title

Mechanism and treatment of ASD related behavior in the Cntnap2 knockout mouse model
$58,000

Funding

58000

Institution

University of California, Los Angeles

Project Title

Effects of oxytocin receptor agonists in mouse models of autism spectrum disorder phenotypes
$48,500

Funding

48500

Institution

University of North Carolina at Chapel Hill

 
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