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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 

Question 4: Short-term Objective B

green dot 4SB. Standardize and validate at least 20 model systems (e.g., cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012. IACC Recommended Budget: $75,000,000 over 5 years.

Projects Found: 94
Total Funding: 21232514
Records
Project Title Funding Funding Institution

Project Title

Functional study of synaptic scaffold protein SHANK3 and autism mouse model
$150,000

Funding

150000

Institution

Duke University

Project Title

The role of SHANK3 in autism spectrum disorders
$0

Funding

0

Institution

Mount Sinai School of Medicine

Project Title

Using zebrafish and chemical screening to define function of autism genes
$0

Funding

0

Institution

Whitehead Institute for Biomedical Research

Project Title

Testing brain overgrowth and synaptic models of autism using NPCs and neurons from patient-derived iPS cells
$315,375

Funding

315375

Institution

University of California, San Francisco

Project Title

Testing brain overgrowth and synaptic models of autism using NPCs and neurons from patient-derived iPS cells
$377,663

Funding

377663

Institution

Salk Institute for Biological Studies

Project Title

Characterization of synaptic and neural circuitry dysfunction underlying ASD-like behaviors using a novel genetic mouse model
$0

Funding

0

Institution

Duke University

Project Title

Quantitative analysis of effect of autism-related genes on behavioral regulation
$102,000

Funding

102000

Institution

University of California, San Francisco

Project Title

Genomic imbalances at the 22q11 locus and predisposition to autism
$0

Funding

0

Institution

Columbia University

Project Title

Shank3 mutant characterization in vivo
$0

Funding

0

Institution

University of Texas Southwestern Medical Center

Project Title

Investigating the effects of chromosome 22q11.2 deletions
$300,000

Funding

300000

Institution

Columbia University

 
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