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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Uncovering the Spectrum of De Novo Mutation in Autism through Whole Genome Sequencing

Principal Investigator

Principal Investigator

Brandler, William

Description

Description

This study aims to sequence the entire genome of individuals with autism in an effort to understand the function of some of the newly identified mutations using cell culture models.

Funder

Funder

Autism Science Foundation

Fiscal Year Funding

Fiscal Year Funding

35000

Current Award Period

Current Award Period

2015-2016

Strategic Plan Question

Strategic Plan Question

Question 3: What Caused This To Happen And Can This Be Prevented?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 3SA. Coordinate and implement the inclusion of approximately 20,000 subjects for genome-wide association studies, as well as a sample of 1,200 for sequencing studies to examine more than 50 candidate genes by 2011. Studies should investigate factors contributing to phenotypic variation across individuals that share an identified genetic variant and stratify subjects according to behavioral, cognitive, and clinical features. IACC Recommended Budget: $43,700,000 over 4 years.

Project Link

Project Link

Uncovering the Spectrum of De Novo Mutation in Autism through Whole Genome Sequencing (External web link)

Institution

Institution

University of California, San Diego

State/Country

State/Country

California

Project Number

Project Number

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

N/A

 
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