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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Genomic influences on development and outcomes in Infants at risk of ASD

Principal Investigator

Principal Investigator

Zwaigenbaum, Lonnie

Description

Description

The High Risk Siblings Research Consortium was established in 2003 as a collaboration among NIH, Autism Speaks and researchers across the world who share a common mission of developing methods of early detection of ASD. The BSRC scientists have pooled their samples of high risk infant siblings of children with an autism diagnosis, who have been carefully monitored and assessed from infancy through early childhood. Research in this area has generated groundbreaking findings regarding risk factors, developmental trajectories and early behavioral and biological markers prior to diagnosis. The goal of this project is to extend our knowledge of early risk factors and biomarkers for ASD by collecting DNA on probands, siblings and parents.

Funder

Funder

Autism Speaks

Fiscal Year Funding

Fiscal Year Funding

0

Current Award Period

Current Award Period

2011-2014

Strategic Plan Question

Strategic Plan Question

Question 3: What Caused This To Happen And Can This Be Prevented?

Strategic Plan Objective

Strategic Plan Objective

Yellow dot: Objective has some degree of funding, but less than the recommended amount. 3SA. Coordinate and implement the inclusion of approximately 20,000 subjects for genome-wide association studies, as well as a sample of 1,200 for sequencing studies to examine more than 50 candidate genes by 2011. Studies should investigate factors contributing to phenotypic variation across individuals that share an identified genetic variant and stratify subjects according to behavioral, cognitive, and clinical features. IACC Recommended Budget: $43,700,000 over 4 years.

Project Link

Project Link

Genomic influences on development and outcomes in Infants at risk of ASD (External web link)

Institution

Institution

University of Alberta

State/Country

State/Country

Canada

Project Number

Project Number

7880

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Genomic influences on development and outcomes in Infants at risk of ASD | 337779 | 2011 | 7880
Genomic influences on development and outcomes in Infants at risk of ASD | 0 | 2014 | 7880
Genomic influences on development and outcomes in Infants at risk of ASD | 337779 | 2013 | 7880
Genomic influences on development and outcomes in Infants at risk of ASD | 0 | 2015 | 7880

 
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