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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Concluding Follow-up of Families Enrolled in the EARLI Cohort

Principal Investigator

Principal Investigator

Newschaffer, Craig

Description

Description

This project completes prospective data collection on enrolled families in the Early Autism Risk Longitudinal Investigation (EARLI), one of the world’s largest autism enriched-risk prospective pregnancy cohorts. This investigation follows remaining families through to baby siblings’ third birthday. These 36 mos outcome data are critically important to maximize the scientific return on studies focusing on discovering environmental ASD risk factors and the mechanisms by which they operate.

Funder

Funder

Autism Speaks

Fiscal Year Funding

Fiscal Year Funding

364000

Current Award Period

Current Award Period

2014-2016

Strategic Plan Question

Strategic Plan Question

Question 3: What Caused This To Happen And Can This Be Prevented?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 3SH. Support at least three studies of special populations or use existing databases to inform our understanding of environmental risk factors for ASD in pregnancy and the early postnatal period by 2012. Such studies could include: o Comparisons of populations differing in geography, gender, ethnic background, exposure history (e.g., prematurity, maternal infection, nutritional deficiencies, toxins), and migration patterns; and o Comparisons of phenotype (e.g., cytokine profiles), in children with and without a history of autistic regression, adverse events following immunization (such as fever and seizures), and mitochondrial impairment. These studies may also include comparisons of phenotype between children with regressive ASD and their siblings. Emphasis on environmental factors that influence prenatal and early postnatal development is particularly of high priority. Epidemiological studies should pay special attention to include racially and ethnically diverse populations. IACC Recommended Budget: $12,000,000 over 5 years.

Project Link

Project Link

Concluding Follow-up of Families Enrolled in the EARLI Cohort (External web link)

Institution

Institution

Drexel University

State/Country

State/Country

Pennsylvania

Project Number

Project Number

9502

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Concluding Follow-up of Families Enrolled in the EARLI Cohort | 60667 | 2014 | 9502

 
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