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Interagency Autism Coordinating Committee (IACC)
Autism Research Database
Office of Autism Research Coordination (OARC)
 
Project Element Element Description

Project Title

Project Title

Sequence-based discovery of genes with pleiotropic effects across diagnostic boundaries and throughout the lifespan

Principal Investigator

Principal Investigator

Talkowski, Michael

Description

Description

A striking number of genes associated with a spectrum of neuropsychiatric disorders (NPD) were found to be disrupted in subjects with ASD and related neurodevelopmental disorders (NDD). Employing innovations in sequencing and bioinformatics developed during his postdoctoral research, Dr. Talkowski seeks to prove that careful genomic approaches can elucidate locations at which some genetic changes confer risk for NPD and NDD.

Funder

Funder

Brain & Behavior Research Foundation

Fiscal Year Funding

Fiscal Year Funding

14998

Current Award Period

Current Award Period

2013-2015

Strategic Plan Question

Strategic Plan Question

Question 3: What Caused This To Happen And Can This Be Prevented?

Strategic Plan Objective

Strategic Plan Objective

Green dot: Objective has greater than or equal to the recommended funding. 3LB. Identify genetic risk factors in at least 50% of people with ASD by 2014. IACC Recommended Budget: $33,900,000 over 6 years.

Project Link

Project Link

No link available.

Institution

Institution

Massachusetts General Hospital

State/Country

State/Country

Massachusetts

Project Number

Project Number

Federal or Private?

Federal or Private?

Private

Received ARRA Funding?

Received ARRA Funding?

No

History/Related Projects

History/Related Projects

Sequence-based discovery of genes with pleiotropic effects across diagnostic boundaries and throughout the lifespan | 0 | 2012 | N/A
Sequence-based discovery of genes with pleiotropic effects across diagnostic boundaries and throughout the lifespan | 29995 | 2014 |
Sequence-based discovery of genes with pleiotropic effects across diagnostic boundaries and throughout the lifespan | 29995 | 2013 |

 
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