The Autism Research Group is investigating the genetic basis of differences in brain development and behaviour seen in autism spectrum disorders (ASD). Using state-of-the-art whole genome sequencing techniques, our investigators are identifying specific genes that can cause autism. Many of these genes influence connections among brain cells, which may account for differences in language and intellectual ability as well as learning style seen in ASD.Our project aims to assess how these genes influence developmental course in children with ASD, building on a national study of newly diagnosed preschoolers followed through to adolescence. We are examining how a child's genetic profile might be used to help anticipate the development of specific physical and mental health challenges in ASD, such as sleep problems and anxiety, to help advise families and tailor supports and interventions. Genetic discoveries can lead the way towards the development of new treatments for autism targeting specific molecular pathways.
Interagency Autism Coordinating Committee (IACC)
Autism Research Database (AFD)
