SFARI is partnering with Roche Pharmaceuticals and the contract research organization PsychoGenics to characterize a prioritized set of mouse models using standard assays and PsychoGenics’ CubeTM Technology. The models that will studied include lines modeling the multigenic copy number deletion of the orthologue of the human 16p11.2 interval, different Shank3 mutations, the CNTNAP2 deletion and, going forward, the line model carrying a mutation in PTEN and the mouse model of Timothy Syndrome (CACNA1C). This project emphasizes automated data collection and analyses that are anticipated to yield an unbiased and comprehensive dataset spanning multiple developmental time-points and domains of functions (e.g., social, cognitive, neurological).
Interagency Autism Coordinating Committee (IACC)
Autism Research Database (AFD)
