Autism Research Database - Location Project Details | IACC

Project Element	Element Description
Project Title Project Title	Molecular Dimorphism in the Locus Coeruleus May Mediate Sex-specific Differences in Psychiatric Disease Risk
Principal Investigator Principal Investigator	Dougherty, Joseph
Description Description	Joseph D. Dougherty, Ph.D., Washington University School of Medicine, will study the basis of sex differences across common psychiatric disorders. While depression and anxiety are more prevalent among women, both autism and attention deficit hyperactivity disorder occur more among men. Dr. Dougherty's team will search for possible differences in brain cell activity, and possibly structure, that give rise to these sex differences. In particular, they will look for genetic differences between men and women in a specific brain region, the locus coeruleus, which is a key treatment target for many psychiatric conditions.
Funder Funder	Brain & Behavior Research Foundation
Funding Country Funding Country	United States
Fiscal Year Funding Fiscal Year Funding	25000
Current Award Period Current Award Period	2016-2018
Strategic Plan Question Strategic Plan Question	Question 2: What is the Biology Underlying ASD?
Funder’s Project Link Funder’s Project Link	No URL available.
Institution Institution	Washington University in St. Louis
Institute Location Institute Location	United States
Project Number Project Number
Government or Private Government or Private	Private
History/Related Projects History/Related Projects	Molecular Dimorphism in the Locus Coeruleus May Mediate Sex-specific Differences in Psychiatric Disease Risk \| 25000 \| 2017 \| Molecular Dimorphism in the Locus Coeruleus May Mediate Sex-specific Differences in Psychiatric Disease Risk \| 50000 \| 2018 \|

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