Autism Research Database - Location Project Details | IACC

Project Element	Element Description
Project Title Project Title	Cellular Mechanisms Controlling White Matter Connectivity: Making Sense of a Genetic Risk Factor for Autism and Schizophrenia
Principal Investigator Principal Investigator	Dragich, Joanna
Description Description	Joanna Molly Dragich, Ph.D., at Columbia University will investigate how biological pathways govern the formation of white matter axonal tracts. The goal is to deepen understanding of how genes can impact cognitive function. Dr. Dragich will study genetic mutations with a gene called WDFY3 that have appeared in patients with schizophrenia and in one patient with ASD. Studying mice carrying these mutations, she hopes to elucidate the mutations’ impact on brain signaling, specifically in white matter.
Funder Funder	Brain & Behavior Research Foundation
Funding Country Funding Country	United States
Fiscal Year Funding Fiscal Year Funding	35000
Current Award Period Current Award Period	2016-2018
Strategic Plan Question Strategic Plan Question	Question 2: What is the Biology Underlying ASD?
Funder’s Project Link Funder’s Project Link	No URL available.
Institution Institution	Columbia University
Institute Location Institute Location	United States
Project Number Project Number
Government or Private Government or Private	Private
History/Related Projects History/Related Projects	Cellular Mechanisms Controlling White Matter Connectivity: Making Sense of a Genetic Risk Factor for Autism and Schizophrenia \| 17500 \| 2017 \| Cellular Mechanisms Controlling White Matter Connectivity: Making Sense of a Genetic Risk Factor for Autism and Schizophrenia \| 0 \| 2018 \|

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