Autism Research Database - Location Project Details | IACC

Project Element	Element Description
Project Title Project Title	In vivo Imaging of Prefrontal Cortical Activity During Social Interactions in Normal and Autism Mice
Principal Investigator Principal Investigator	Fu, Min
Description Description	Min Fu, Ph.D., at Duke University will investigate core symptoms of autism spectrum disorder: social interaction and social communication deficits. Studies have shown that the prefrontal cortex (PFC plays a crucial role in social cognition. How PFC neurons mediate social recognition and regulate social behaviors remains largely unknown, however. Dr. Fu will record large populations of PFC neurons using a brain imaging system that allows mice to move freely (required for social interaction behaviors. Results may provide novel insights into neural substrates underlying social recognition, and how this process might be abnormally altered in mouse models of autism.
Funder Funder	Brain & Behavior Research Foundation
Funding Country Funding Country	United States
Fiscal Year Funding Fiscal Year Funding	35000
Current Award Period Current Award Period	2016-2018
Strategic Plan Question Strategic Plan Question	Question 2: What is the Biology Underlying ASD?
Funder’s Project Link Funder’s Project Link	No URL available.
Institution Institution	Duke University
Institute Location Institute Location	United States
Project Number Project Number
Government or Private Government or Private	Private
History/Related Projects History/Related Projects	In vivo Imaging of Prefrontal Cortical Activity During Social Interactions in Normal and Autism Mice \| 17500 \| 2017 \| In vivo Imaging of Prefrontal Cortical Activity During Social Interactions in Normal and Autism Mice \| 17500 \| 2018 \|

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