Autism Research Database - Principal Investigator Project Details | IACC

Project Element	Element Description
Project Title Project Title	a-Actinin Regulates Postsynaptic AMPAR Targeting by Anchoring PSD-95
Principal Investigator Principal Investigator	Matt, Lucas
Description Description	Lucas Matt, Ph.D., University of California, Davis, is studying a major ASD gene, PSD-95, the central structural element of post-synaptic excitatory synapses. His focus is a factor called a-Actinin, that he thinks is responsible for PSD-95 localization. Defining how PSD-95 is anchored will fill a crucial gap in information about synaptic structure and could aid in the development of new ASD therapies.
Funder Funder	Brain & Behavior Research Foundation
Funding Country Funding Country	United States
Fiscal Year Funding Fiscal Year Funding	19748
Current Award Period Current Award Period	2014-2016
Strategic Plan Question Strategic Plan Question	Question 2: What is the Biology Underlying ASD?
Funder’s Project Link Funder’s Project Link	No URL available.
Institution Institution	University of Tuebingen
Institute Location Institute Location	Germany
Project Number Project Number
Government or Private Government or Private	Private
History/Related Projects History/Related Projects	a-Actinin Regulates Postsynaptic AMPAR Targeting by Anchoring PSD-95 \| 0 \| 2013 \| a-Actinin Regulates Postsynaptic AMPAR Targeting by Anchoring PSD-95 \| 0 \| 2013 \| a-Actinin Regulates Postsynaptic AMPAR Targeting by Anchoring PSD-95 \| 30000 \| 2014 \| a-Actinin Regulates Postsynaptic AMPAR Targeting by Anchoring PSD-95 \| 15000 \| 2015 \|

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