Autism Research Database - Principal Investigator Project Details

Project Element	Element Description
Project Title Project Title	Calcium Channels as a Core Mechanism in the Neurobiology of ASD
Principal Investigator Principal Investigator	Nedelcu, Daniel
Description Description	Mutations of the SHANK gene are known to be an important risk factor for autism, and pharmacological manipulation of the gene may offer some therapeutic benefit. This study will explore how this gene affects a certain type of channel known to be important in cell-to-cell communication. These results may provide targets for pharmacological modulation and thus lead to immediate therapeutic benefits for treating individuals with autism.
Funder Funder	Autism Science Foundation
Funding Country Funding Country	United States
Fiscal Year Funding Fiscal Year Funding	0
Current Award Period Current Award Period	2015-2016
Strategic Plan Question Strategic Plan Question	Question 2: What is the Biology Underlying ASD?
Funder’s Project Link Funder’s Project Link	External Project Page
Institution Institution	Massachusetts General Hospital
Institute Location Institute Location	United States
Project Number Project Number
Government or Private Government or Private	Private
History/Related Projects History/Related Projects	Calcium Channels as a Core Mechanism in the Neurobiology of ASD \| 35000 \| 2015 \| Calcium Channels as a Core Mechanism in the Neurobiology of ASD \| 0 \| 2017 \|