Autism Research Database - Principal Investigator Project Details | IACC

Project Element	Element Description
Project Title Project Title	Role of Serotonin Signaling during Neural Circuitry Formation in Autism Spectrum Disorders
Principal Investigator Principal Investigator	Yoshii, Akira
Description Description	Akira Yoshii, M.D., Ph.D., Massachusetts Institute of Technology will study a genetic syndrome called Tuberous Sclerosis Complex (TSC) that sometimes accompanies ASD. Using two-photon microscopy and molecular imaging, he will seek to determine if serotonin synapses are dysregulated in TSC, providing information on the causal relationship between dysregulated serotonin function during early brain development and ASD.
Funder Funder	Brain & Behavior Research Foundation
Funding Country Funding Country	United States
Fiscal Year Funding Fiscal Year Funding	15000
Current Award Period Current Award Period	2014-2016
Strategic Plan Question Strategic Plan Question	Question 2: What is the Biology Underlying ASD?
Funder’s Project Link Funder’s Project Link	No URL available.
Institution Institution	Massachusetts Institute of Technology
Institute Location Institute Location	United States
Project Number Project Number
Government or Private Government or Private	Private
History/Related Projects History/Related Projects	Role of Serotonin Signaling during Neural Circuitry Formation in Autism Spectrum Disorders \| 0 \| 2013 \| Role of Serotonin Signaling during Neural Circuitry Formation in Autism Spectrum Disorders \| 0 \| 2014 \| Role of Serotonin Signaling during Neural Circuitry Formation in Autism Spectrum Disorders \| 0 \| 2015 \| Role of Serotonin Signaling during Neural Circuitry Formation in Autism Spectrum Disorders \| 45000 \| 2017 \|

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