Autism Research Database - Principal Investigator Project Details | IACC

Project Element	Element Description
Project Title Project Title	Jones Lab Collaboration with the Autism Speaks (PACT)
Principal Investigator Principal Investigator	Jones, Carrie
Description Description	This project represents the addition of a new site to the Preclinical Autism Consortium for Therapeutics (PACT), a focused preclinical target selection and prosecution effort to de-risk the discovery and development of medicines aimed at treating the core diagnostic symptoms of autism. Studies at this site will evaluate different rat models with genetic mutations associated with autism to provide strong, replicable, corroborative behavioral and physiological phenotypes relevant to the symptoms of autism observed in patient populations. The project will identify robust phenotypes that may then be employed to evaluate selected compounds for symptom reversal. Demonstrating efficacy in multiple rodent models and standardized tests will increase confidence in specific pharmacological mechanisms of action for autism clinical trials.
Funder Funder	Autism Speaks
Funding Country Funding Country	United States
Fiscal Year Funding Fiscal Year Funding	0
Current Award Period Current Award Period	2014-2016
Strategic Plan Question Strategic Plan Question	Question 7: How Do We Continue to Build, Expand, and Enhance the Infrastructure System to Meet the Needs of the ASD Community?
Funder’s Project Link Funder’s Project Link	External Project Page
Institution Institution	Vanderbilt University
Institute Location Institute Location	United States
Project Number Project Number	9489
Government or Private Government or Private	Private
History/Related Projects History/Related Projects	Jones Lab Collaboration with the Autism Speaks (PACT) \| 144372 \| 2015 \| 9489 Jones Lab Collaboration with the Autism Speaks (PACT) \| 144372 \| 2014 \| 9489

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