Autism Research Database - Principal Investigator Project Details | IACC

Project Element	Element Description
Project Title Project Title	SINEUPs Technology to Rescue CHD8 Haploinsufficiency: Possible New Avenues of Therapeutical Intervention for Autism Spectrum Disorders (ASD
Principal Investigator Principal Investigator	Biagioli, Marta
Description Description	Marta Biagioli, Ph.D., at the University of Trento, Italy, will investigate a novel gene therapy for autism spectrum disorder (ASD. A genetic mutation causing a reduction of a protein called CHD8 has been shown in several studies to be linked to ASD. Dr. Biagioli aims to develop innovative RNA tools to increase CHD8 expression and reverse alterations observed in both cellular and animal models of ASD.
Funder Funder	Brain & Behavior Research Foundation
Funding Country Funding Country	United States
Fiscal Year Funding Fiscal Year Funding	35000
Current Award Period Current Award Period	2016-2018
Strategic Plan Question Strategic Plan Question	Question 3: What Causes ASD, and Can Disabling Aspects of ASD be Prevented or Preempted?
Funder’s Project Link Funder’s Project Link	No URL available.
Institution Institution	University of Trento
Institute Location Institute Location	Italy
Project Number Project Number
Government or Private Government or Private	Private
History/Related Projects History/Related Projects	SINEUPs Technology to Rescue CHD8 Haploinsufficiency: Possible New Avenues of Therapeutical Intervention for Autism Spectrum Disorders (ASD \| 17500 \| 2017 \| SINEUPs Technology to Rescue CHD8 Haploinsufficiency: Possible New Avenues of Therapeutical Intervention for Autism Spectrum Disorders (ASD \| 17500 \| 2018 \|

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