Autism Research Database - Principal Investigator Project Details | IACC

Project Element	Element Description
Project Title Project Title	Modulation of the Oxytocin System in a Mouse Model of Autism Spectrum Disorder (ASD
Principal Investigator Principal Investigator	Penagarikano, Olga
Description Description	Olga Penagarikano, Ph.D., of the University of the Basque Country, Spain, will study dysfunction in the release of the neurotransmitter oxytocin, which is associated with social deficits in autism and psychiatric disorders. This project will expand on past findings revealing the social effects of oxytocin to probe how oxytocin interacts with two neurotransmitters extensively linked to social behavior: dopamine and serotonin. Looking at brain activity in mice, the team will also examine how oxytocin and its interactions with the dopamine and serotonin systems are affected by environmental factors. They hope to help identify candidates for therapeutic intervention early in human development that may improve social deficits.
Funder Funder	Brain & Behavior Research Foundation
Funding Country Funding Country	United States
Fiscal Year Funding Fiscal Year Funding	32158
Current Award Period Current Award Period	2016-2019
Strategic Plan Question Strategic Plan Question	Question 4: Which Treatments and Interventions Will Help?
Funder’s Project Link Funder’s Project Link	No URL available.
Institution Institution	University of the Basque Country
Institute Location Institute Location	Spain
Project Number Project Number
Government or Private Government or Private	Private
History/Related Projects History/Related Projects	Modulation of the Oxytocin System in a Mouse Model of Autism Spectrum Disorder (ASD \| 16079 \| 2017 \| Modulation of the Oxytocin System in a Mouse Model of Autism Spectrum Disorder (ASD \| 16079 \| 2018 \| Modulation of the Oxytocin System in a Mouse Model of Autism Spectrum Disorder (ASD) \| 0 \| 2019 \|

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