|Project Title||Principal Investigator||Institution|
|Informational and neural bases of empathic accuracy in autism spectrum disorder||Zaki, Jamil||Columbia University|
|Functional MRI of attention regulation in people with and without autism||Vaidya, Chandan||Georgetown University|
|Family characterization network - 2||Tager-Flusberg, Helen||Boston University School of Medicine|
|Phonological processing in the autism spectrum||Stewart, Mary||Heriot-Watt University|
|Autism spectrum disorder and the visual analysis of human motion||Shiffrar, Maggie||Rutgers, The State University of New Jersey|
|Visual perspective-taking and the acquisition of American Sign Language by deaf children with autism||Shield, Aaron||University of Texas at Austin|
|Impacts of parenting adolescents & adults with autism||Seltzer, Marsha||University of Wisconsin - Madison|
|Neural mechanisms for social cognition in ASD||Saxe, Rebecca||Massachusetts Institute of Technology|
|Family characterization network - 1||Santangelo, Susan||Massachusetts General Hospital|
|Gamma band dysfunction as a local neuronal connectivity endophenotype in autism||Rojas, Donald||University of Colorado Denver|
|Psychophysiological mechanisms of emotion perception||Robins, Diana||Georgia State University|
|Neural substrate of language and social cognition: Autism and typical development||Redcay, Elizabeth||Massachusetts Institute of Technology|
|A longitudinal MRI study of infants at risk for autism||Piven, Joseph||University of North Carolina at Chapel Hill|
|A longitudinal MRI study of infants at risk for autism- Supplemental||Piven, Joseph||University of North Carolina at Chapel Hill|
|Longitudinal neurogenetics of atypical social brain development in autism||Pelphrey, Kevin||Yale University|
|Electrical measures of functional cortical connectivity in autism||Murias, Michael||University of Washington|
|Behavioral and functional neuroimaging investigations of visual perception and cognition in autistics||Mottron, Laurent||Université de Montréal|
|Novel approaches for investigating the neurology of autism: Detailed morphometric analysis and correlation with motor impairment||Mostofsky, Stewart||Kennedy Krieger Institute|
|FMRI studies of cerebellar functioning in autism||Mosconi, Matthew||University of Illinois at Chicago|
|Neural correlates of social exchange and valuation in autism||Montague, P. Read||Baylor College of Medicine|
|Neural correlates of serotonin transporter gene polymorphisms and social impairment in ASD||Monk, Christopher||University of Michigan|
|Linguistic perspective-taking in adults with high-functioning autism: Investigation of the mirror neuron system||Mizuno, Akiko||Carnegie Mellon University|
|FMRI evidence of genetic influence on rigidity in ASD||Lee, Jillian||University of Michigan|
|Quantifying white matter connectivity in autism||Lainhart, Janet||University of Utah|
|Investigation of the link between early brain enlargement and abnormal functional connectivity in autism spectrum disorders||Kleinhans, Natalia||University of Washington|
|IACC Strategic Plan Objectives||2008||2009||2010||2011||2012||Total|
|Complete a large-scale, multidisciplinary, collaborative project that longitudinally and comprehensively examines how the biological, clinical, and developmental profiles of individuals, with a special emphasis on females, youths, and adults with ASD, change over time as compared to typically developing people by 2020.
IACC Recommended Budget: $126,200,000 over 12 years
|2.L.A. Funding: The recommended budget was partially met.
Progress: Several projects have been funded in this area, and the ACE Network continues to collect data relevant to this objective.
Remaining Gaps, Needs and Opportunities: Though this research is underway, more clinical studies are needed over a longer trajectory to identify issues faced as people with ASD age, especially with regard to risk factors for other medical conditions. Another remaining need is that of standardization of data collection and analysis methods.