|Project Title||Principal Investigator||Institution|
|Double blind placebo controlled evaluation of fluconazole||Granpeesheh, Doreen||Center for Autism and Related Disorders|
|Double blind placebo controlled trial of hyperbaric oxygen||Granpeesheh, Doreen||Center for Autism and Related Disorders|
|Acupressure and acupuncture as an intervention with children with autism||Warren, Lana||Kennedy Krieger Institute|
|Parents and professionals attitudes to dietary interventions in ASD (PADIA)||Le Couteur, Ann||Newcastle University|
|Probiotics and vitamin D in ASD||Stubbs, Gene||Oregon Health & Science University|
|Safety and efficacy of complementary and alternative medicine for autism spectrum disorders||Bent, Stephen||University of California, San Francisco|
|Omega 3 fatty acids in the treatment of children with autism spectrum disorders||Novotny, Sherie||University of Medicine & Dentistry of New Jersey - Robert Wood Johnson Medical School|
|Raising glutathione levels in children with autism||Kern, Janet||University of Texas|
|IACC Strategic Plan Objectives||2008||2009||2010||2011||2012||Total|
|Test safety and efficacy of at least five widely used interventions (e.g., nutrition, medications, assisted technologies, sensory integration, medical procedures) that have not been rigorously studied for use in ASD by 2012.
IACC Recommended Budget: $27,800,000 over 5 years
|4.S.C. Funding: The recommended budget was partially met.
Progress: Several projects were funded in this area, but more work is needed, as this is an area of significant public interest.
Remaining Gaps, Needs, and Opportunities: Experts discussed the best balance between developing new treatments and testing current treatments that lack evidence, especially when funds are limited and conclusive clinical trials are expensive. The group noted that interventions for minimally verbal children are needed; some projects on assistive communication technologies, robotics and speech processing technology to assist with social communication training are funded, but more are needed. There are other projects related to minimally verbal autism in objective 4.S.G. Small pilot studies on nutritional therapies (i.e., GFCF diet studies) have been conducted with inconclusive outcomes, demonstrating the necessity for further exploration of nutritional interventions. Future emphasis on scientific investment in sensory integration and assisted technologies is needed.