Strategic Plan Objective Detail
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Question 1: Long-term Objective A  

Fiscal Year: 2010

Green dot: Objective has greater than or equal to the recommended funding.1LA. Identify behavioral and biological markers that separately, or in combination, accurately identify, before age 2, one or more subtypes of children at risk for developing ASD, and evaluate whether these risk markers or profiles can improve early identification through heightened developmental monitoring and screening by 2014. IACC Recommended Budget: $33,300,000 over 5 years.

Download 2010 Question 1: Long-term Objective A projects (EXCEL)
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Institution
Biomarkers for autism and for gastrointestinal and sleep problems in autism Anderson, George Yale University
ACE Center: Gaze perception abnormalities in infants with ASD Chawarska, Katarzyna Yale University
Prospective study of infants at high risk for autism Chawarska, Katarzyna Yale University
Model diagnostic lab for infants at risk for autism Klin, Ami Yale University
Brain-behavior growth charts of altered social engagement in ASD infants Klin, Ami Yale University
Physical and clinical infrastructure for research on infants-at-risk for autism at Yale Klin, Ami Yale University
ACE Center: Assessment Core Klin, Ami Yale University
The ontogeny of social visual engagement in infants at risk for autism Klin, Ami Yale University
Misregulation of BDNF in autism spectrum disorders Hempstead, Barbara Weill Cornell Medical College
Developmental characteristics of MRI diffusion tensor pathway changes in autism Conturo, Thomas Washington University
Observational and electrophysiological assessments of temperament in infants at risk for autism spectrum disorders Burner, Karen University of Washington
A longitudinal 3-D MRSI study of infants at high risk for autism Dager, Stephen University of Washington
Neurophysiological indices of risk and outcome in autism Webb, Sara University of Washington
ACE Center: Linguistic and social responses to speech in infants at risk for autism Kuhl, Patricia University of Washington
Early social and emotional development in toddlers at genetic risk for autism Campbell, Susan University of Pittsburgh
Defining high and low risk expression of emotion in infants at risk for autism Hannigen, Sarah University of Pittsburgh
Early identification of autism: A prospective study Iverson, Jana University of Pittsburgh
Temporal coordination of social communicative behaviors in infant siblings of children with autism Parlade, Meaghan University of Pittsburgh
Supplement to NIH ACE Network grant: "A longitudinal MRI study of infants at risk for autism" Piven, Joseph University of North Carolina at Chapel Hill
ACE Network: A longitudinal MRI study of infants at risk for autism Piven, Joseph University of North Carolina at Chapel Hill
Validation study of atypical dynamic pupillary light reflex as a biomarker for autism Yao, Gang; Miles, Judith; Christ, Shawn University of Missouri
The emergence of emotion regulation in children at-risk for autism spectrum disorder Ekas, Naomi University of Miami
Pupil size and circadian salivary variations in autism spectrum disorder Colombo, John University of Kansas
Abnormal vestibulo-ocular reflexes in autism: A potential endophenotype White, Keith University of Florida
ACE Center: MRI studies of early brain development in autism Courchesne, Eric University of California, San Diego