Strategic Plan Objective Detail
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Question 3: Short-term Objective C  

$4,824,779.00
Fiscal Year: 2010

Yellow dot: Objective has some degree of funding, but less than the recommended amount.3SC. Initiate efforts to expand existing large case-control and other studies to enhance capabilities for targeted gene – environment research by 2011. IACC Recommended Budget: $27,800,000 over 5 years.

Download 2010 Question 3: Short-term Objective C projects (EXCEL)
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Project Title Principal Investigator Institution
Genetics and gene-environment interactions in a Korean epidemiological sample of autism Kim, Young Shin Yale University
Center for Genomic and Phenomic Studies in Autism Lajonchere, Clara University of Southern California
Vitamin D status and autism spectrum disorder: Is there an association? Hammock, Bruce University of California, Davis
The CHARGE Study: Childhood Autism Risks from Genetics and the Environment Hertz-Picciotto, Irva University of California, Davis
UC Davis Children's Environmental Health and Disease Prevention Research Center Pessah, Isaac University of California, Davis
Project 1: Effect of multi-level environmental exposure on birth outcomes Tager, Ira University of California, Berkeley
Prenatal and neonatal biologic markers for autism Croen, Lisa Kaiser Foundation Research Institute
Genome-wide environment interaction study for autism: The SEED study Fallin, Margaret; Newschaffer, Craig Johns Hopkins University

Objective Cumulative Funding Table

IACC Strategic Plan Objective 2008 2009 2010 2011 2012 Total
Initiate efforts to expand existing large case-control and other studies to enhance capabilities for targeted gene-environment research by 2011.

IACC Recommended Budget: $27,800,000 over 5 years
3.4
$4,703,867
4 projects

3.S.C
$8,033,454
9 projects

3.S.C
$4,824,779
8 projects

3.S.C
$5,714,408
10 projects

3.S.C
$3,626,803
9 projects

$26,903,311
3.S.C. Funding: The recommended budget was nearly met, but work still needs to continue on this objective.

Progress: The funding allocated to this area so far has primarily supported building infrastructure that can now be expanded to include more subjects, more data, and more analytical projects. Studies such as the MARBLES (Markers of Autism Risk in Babies Learning Early Signs) cohort study and the CHARGE (Childhood Autism Risks from Genetics and the Environment) study are included under this objective.

Remaining Gaps, Needs, and Opportunities: Continued benefit will be derived from past investments as these resources are expanded and pooled.