Strategic Plan Objective Detail
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Question 1: Long-term Objective A  

Fiscal Year: 2010

Green dot: Objective has greater than or equal to the recommended funding.1LA. Identify behavioral and biological markers that separately, or in combination, accurately identify, before age 2, one or more subtypes of children at risk for developing ASD, and evaluate whether these risk markers or profiles can improve early identification through heightened developmental monitoring and screening by 2014. IACC Recommended Budget: $33,300,000 over 5 years.

Download 2010 Question 1: Long-term Objective A projects (EXCEL)
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Institution
Model diagnostic lab for infants at risk for autism Klin, Ami Yale University
Multiplexed suspension arrays to investigate newborn and childhood blood samples for potential immune biomarkers of autism Vogt, Robert Centers for Disease Control and Prevention (CDC)
Neurobehavioral research on infants at risk for SLI and autism Tager-Flusberg, Helen; Nelson, Charles Boston University Medical Campus
Neurophysiological indices of risk and outcome in autism Webb, Sara University of Washington
Neurophysiological investigation of language acquisition in infants at risk for ASD Seery, Anne Boston University
Observational and electrophysiological assessments of temperament in infants at risk for autism spectrum disorders Burner, Karen University of Washington
Oxytocin biology and the social deficits of autism spectrum disorders Parker, Karen Stanford University
Physical and clinical infrastructure for research on infants-at-risk for autism at Yale Klin, Ami Yale University
Placental vascular tree as biomarker of autism/ASD risk Salafia, Carolyn Research Foundation for Mental Hygiene, Inc.
Prospective study of infants at high risk for autism Chawarska, Katarzyna Yale University
Pupil size and circadian salivary variations in autism spectrum disorder Colombo, John University of Kansas
RNA expression studies in autism spectrum disorders Kunkel, Louis Children's Hospital Boston
Signatures of gene expression in autism spectrum disorders Kunkel, Louis Children's Hospital Boston
Studying the biology and behavior of autism at 1-year: The Well-Baby Check-Up approach Pierce, Karen University of California, San Diego
Supplement to NIH ACE Network grant: "A longitudinal MRI study of infants at risk for autism" Piven, Joseph University of North Carolina at Chapel Hill
Temperament, emotional expression, and emotional self-regulation in relation to later ASD diagnosis Wozniak, Robert Bryn Mawr College
Temporal coordination of social communicative behaviors in infant siblings of children with autism Parlade, Meaghan University of Pittsburgh
The emergence of emotion regulation in children at-risk for autism spectrum disorder Ekas, Naomi University of Miami
The ontogeny of social visual engagement in infants at risk for autism Klin, Ami Yale University
Validation study of atypical dynamic pupillary light reflex as a biomarker for autism Yao, Gang; Miles, Judith; Christ, Shawn University of Missouri