Strategic Plan Objective Detail
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Question 3: Long-term Objective B  

Fiscal Year: 2010

Green dot: Objective has greater than or equal to the recommended funding.3LB. Identify genetic risk factors in at least 50% of people with ASD by 2014. IACC Recommended Budget: $33,900,000 over 6 years.

Download 2010 Question 3: Long-term Objective B projects (EXCEL)
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Institution
The frequency of polymorphisms in maternal- and paternal-effect genes in autism spectrum Levine, Arnold Princeton University
Hypocholesterolemic autism spectrum disorder Porter, Forbes National Institutes of Health
Genetic epidemiology of complex traits Bailey-Wilson, Joan National Institutes of Health
The transcription factor PLZF: A possible genetic link between immune dysfunction and autism Sant'Angelo, Derek Memorial Sloan-Kettering Cancer Center
The role of the neurexin 1 gene in susceptibility to autism Gusella, James Massachusetts General Hospital/Harvard Medical School
Comprehensive follow-up of novel autism genetic discoveries Daly, Mark Massachusetts General Hospital
Investigation of genes involved in synaptic plasticity in Iranian families with ASD Santangelo, Susan Massachusetts General Hospital
A recurrent genetic cause of autism Gusella, James Massachusetts General Hospital
Genes disrupted by balanced genomic rearrangements in autism spectrum disorders Gusella, James Massachusetts General Hospital
Role of TSC/mTOR signaling pathway in autism and autism spectrum disorders Ramesh, Vijaya Massachusetts General Hospital
Integrative genetic analysis of autistic brains Arking, Dan Johns Hopkins University School of Medicine
The role of contactin-associated protein-like 2 (CNTNAP2) and other novel genes in autism Chakravarti, Aravinda Johns Hopkins University School of Medicine
The role of retrotransposons in autism spectrum disorders Kazazian, Haig Johns Hopkins University
Understanding glutamate signaling defects in autism spectrum disorders Wang, Tao Johns Hopkins University
Illumina, Inc. No PI listed Illumina, Inc.
Population genetics to improve homozygosity mapping and mapping in admixed groups Williams, Amy Harvard Medical School
Dense mapping of candidate regions linked to autistic disorder Gregersen, Peter Feinstein Institute For Medical Research
Simons Simplex Collection Site Lese Martin, Christa Emory University
Comprehensive genetic variation detection to assess the role of the X chromosome in autism Warren, Stephen Emory University
Whole-genome sequencing for rare highly penetrant gene variants in schizophrenia Goldstein, David Duke University
Simons Simplex Collection Site Peterson, Bradley Columbia University
Genetic basis of autism Wigler, Michael Cold Spring Harbor Laboratory
Genome-wide association study of autism characterized by developmental regression Molloy, Cynthia Cincinnati Children's Hospital Medical Center
Potential role of non-coding RNAs in autism Talebizadeh, Zohreh Children's Mercy Hospitals And Clinics
Gene expression profiling of autism spectrum disorders Collins, Christin Children's Hospital Boston