|Project Title||Principal Investigator||Institution|
|Risk and protective factors in the development of associated symptoms in autism||Estes, Annette||University of Washington|
|Efficacy of community-based instruction and supported employment on the competitive employment outcomes on transition-age youth with autism||Wehman, Paul||Virginia Commonwealth University|
|An examination of the effectiveness of manipulative letter instruction on decoding skills of young children with autism||Conroy, Maureen||Virginia Commonwealth University|
|Early pharmacotherapy guided by biomarkers in autism||Chugani, Diane||Wayne State University|
|A randomized controlled trial of two treatments for verbal communication||Paul, Rhea||Yale Child Study Center|
|IACC Strategic Plan Objectives||2008||2009||2010||2011||2012||Total|
|Launch randomized controlled trials of interventions including biological signatures and other measures to predict response, and monitor quality of life and functional outcomes in each of the following groups:
Total IACC Recommended Budget: $66,000,000 over 5 years
|4.3 & 4.4
16 projects & 30 projects
|4.S.F. Funding: The recommended budget was partially met.
Progress: The investment in projects under this objective is making good progress toward the recommended amount, with more than 20 projects funded in 2011 and 2012.
Remaining Gaps, Needs, and Opportunities: Current projects in this area are restricted to small pilot studies, which are essential to establishing a foundation prior to expansion to larger scale work. Thus, increased investment in this area is important.Â It should be noted that most RCTs in the future will incorporate some aspect of biological signatures (thus potentially presenting a challenge to future coding of projects).