Strategic Plan Objective Detail
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Question 2: Objective 5  

$8,523,806.09
Fiscal Year: 2008

Yellow dot: Objective has some degree of funding, but less than the recommended amount.2.5 Complete a large-scale, multi-disciplinary, collaborative project that longitudinally and comprehensively examines how the biological, clinical, and developmental profiles of children, with a special emphasis on females, youths, and adults with ASD change over time as compared to typically developing people by 2020. IACC Recommended Budget: $126,200,000 over 12 years.

Download 2008 Question 2: Objective 5 projects (EXCEL)
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Institution
Quantifying white matter connectivity in autism Lainhart, Janet University of Utah
FMRI evidence of genetic influence on rigidity in ASD Lee, Jillian University of Michigan
Linguistic perspective-taking in adults with high-functioning autism: Investigation of the mirror neuron system Mizuno, Akiko Carnegie Mellon University
Neural correlates of serotonin transporter gene polymorphisms and social impairment in ASD Monk, Christopher University of Michigan
Neural correlates of social exchange and valuation in autism Montague, P. Read Baylor College of Medicine
FMRI studies of cerebellar functioning in autism Mosconi, Matthew University of Illinois at Chicago
Novel approaches for investigating the neurology of autism: Detailed morphometric analysis and correlation with motor impairment Mostofsky, Stewart Kennedy Krieger Institute
Behavioral and functional neuroimaging investigations of visual perception and cognition in autistics Mottron, Laurent Université de Montréal
Electrical measures of functional cortical connectivity in autism Murias, Michael University of Washington
Longitudinal neurogenetics of atypical social brain development in autism Pelphrey, Kevin Yale University
A longitudinal MRI study of infants at risk for autism- Supplemental Piven, Joseph University of North Carolina at Chapel Hill
A longitudinal MRI study of infants at risk for autism Piven, Joseph University of North Carolina at Chapel Hill
Neural substrate of language and social cognition: Autism and typical development Redcay, Elizabeth Massachusetts Institute of Technology
Psychophysiological mechanisms of emotion perception Robins, Diana Georgia State University
Gamma band dysfunction as a local neuronal connectivity endophenotype in autism Rojas, Donald University of Colorado Denver
Family characterization network - 1 Santangelo, Susan Massachusetts General Hospital
Neural mechanisms for social cognition in ASD Saxe, Rebecca Massachusetts Institute of Technology
Impacts of parenting adolescents & adults with autism Seltzer, Marsha University of Wisconsin - Madison
Visual perspective-taking and the acquisition of American Sign Language by deaf children with autism Shield, Aaron University of Texas at Austin
Autism spectrum disorder and the visual analysis of human motion Shiffrar, Maggie Rutgers, The State University of New Jersey
Phonological processing in the autism spectrum Stewart, Mary Heriot-Watt University
Family characterization network - 2 Tager-Flusberg, Helen Boston University School of Medicine
Functional MRI of attention regulation in people with and without autism Vaidya, Chandan Georgetown University
Informational and neural bases of empathic accuracy in autism spectrum disorder Zaki, Jamil Columbia University

Objective Cumulative Funding Table

IACC Strategic Plan Objectives 2008 2009 2010 2011 2012 Total
Complete a large-scale, multidisciplinary, collaborative project that longitudinally and comprehensively examines how the biological, clinical, and developmental profiles of individuals, with a special emphasis on females, youths, and adults with ASD, change over time as compared to typically developing people by 2020.

IACC Recommended Budget: $126,200,000 over 12 years
2.5
$8,523,806
49 projects

2.L.A
$2,721,384
6 projects

2.L.A
$2,283,875
6 projects

2.L.A
$972,559
5 projects

2.L.A
$6,160,017
9 projects

$20,661,641
2.L.A. Funding: The recommended budget was partially met.

Progress: Several projects have been funded in this area, and the ACE Network continues to collect data relevant to this objective.

Remaining Gaps, Needs and Opportunities: Though this research is underway, more clinical studies are needed over a longer trajectory to identify issues faced as people with ASD age, especially with regard to risk factors for other medical conditions. Another remaining need is that of standardization of data collection and analysis methods.