Strategic Plan Objective Detail
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Question 2: Short-term Objective D  

Fiscal Year: 2010

Green dot: Objective has greater than or equal to the recommended funding.2SD. Launch three studies that target improved understanding of the underlying biological pathways of genetic conditions related to autism (e.g. Fragile X, Rett syndrome, tuberous sclerosis complex) and how these conditions inform risk assessment and individualized intervention by 2012. IACC Recommended Budget: $9,000,000 over 5 years.

Download 2010 Question 2: Short-term Objective D projects (EXCEL)
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Institution
Augmentation of the cholinergic system in fragile X syndrome: A double-blind placebo study Reiss, Allan Stanford University
Angelman syndrome (AS) Percy, Alan University of Alabama at Birmingham
A longitudinal MRI study of brain development in fragile X syndrome Hazlett, Heather University of North Carolina at Chapel Hill
Allelic choice in Rett syndrome Donohoe, Mary Winifred Masterson Burke Medical Research Institute
Activity-dependent phosphorylation of MeCP2 Ebert, Daniel Harvard Medical School
Aberrant synaptic function caused by TSC mutation in autism Sulzer, David Columbia University
Aberrant synaptic form and function due to TSC-mTOR-related mutation in autism spectrum disorders Sulzer, David Columbia University