Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Neural dissection of hyperactivity/inattention in autism  

Although many school-age children with autism spectrum disorders are also hyperactive and inattentive, which further limits their school and social functioning, researchers have been unable to determine whether the brain processes responsible for such ADHD-like symptoms are the same as in typical ADHD or whether they reflect distinct brain processes. Using new functional magnetic resonance imaging (fMRI) methods to measure spontaneous brain function (functional connectivity of neural circuits), this study will disentangle these issues in three groups of children: children with an autism spectrum disorder diagnosis, children with ADHD, and typically developing children to use as experimental controls. If successful, the types of brain mechanisms that are involved in hyperactivity and inattention in children with autism will be better understood, and then this new knowledge can be applied to guide targeted treatment studies. Project Status


Funder National Institutes of Health
Fiscal Year Funding $1,179,863.00
Project Number 1R01HD065282-01
Principal Investigator Castellanos, Francisco Xavier
Received ARRA Funding? Yes
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Strategic Plan Objective New! Green dot: Objective has greater than or equal to the recommended funding. 2SE. Launch three studies that target the underlying biological mechanisms of co-occurring conditions with autism including seizures/epilepsy, sleep disorders and familial autoimmune disorders by 2012. IACC Recommended Budget: $9,000,000 over 5 years.
Federal or Private? Federal
Institution New York University School of Medicine
State/Country New York
Web Link 1 Neural dissection of hyperactivity/inattention in autism (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Neural dissection of hyperactivity/inattention in autism | $1,117,595.00 | 2010 | 5R01HD065282-02