Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Prospective study of infants at high risk for autism  

Autism is a complex congenital neurodevelopmental disorder with recurrence risk in younger siblings of affected individuals reaching at least 8%. Despite parental concern arising in children as young as one year old, evidence regarding expression of autism in the first two years of life is very limited. This prospective study will examine development of infant siblings of children with autism contrasted with that of typically developing infants and infants at risk for developmental delays without autistic features. The infants will complete a series of conceptually linked assessment procedures targeting perceptual, social, communicative, cognitive (verbal and nonverbal), motor, and adaptive development at 3, 6, 9,12, 18, and 24 months of age, with confirmatory diagnostic assessment at 36 months. This research could inform early diagnosis and treatment as well as elucidate underlying mechanisms of ASD through identification of primary symptoms and distortions in the sequence of skills acquisition. Project Status


Funder National Institutes of Health
Fiscal Year Funding $286,887.00
Project Number 5P01HD003008-41
Principal Investigator Chawarska, Katarzyna
Received ARRA Funding? No
Strategic Plan Question Question 1: When Should I Be Concerned? (Diagnosis)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 1LA. Identify behavioral and biological markers that separately, or in combination, accurately identify, before age 2, one or more subtypes of children at risk for developing ASD by 2014. IACC Recommended Budget: $33,300,000 over 5 years.
Federal or Private? Federal
Institution Yale University
State/Country Connecticut
Web Link 1 Prospective study of infants at high risk for autism (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Prospective study of infants at high risk for autism | $292,249.00 | 2010 | 5P01HD003008-42
Prospective study of infants at high risk for autism | $278,814.00 | 2008 | P01HD003008-40