Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Genetics of autism intermediate phenotypes  

The purpose of this project is to search for susceptibility genes for autism using intermediate phenotypes. Blood samples will be collected from a total of 800 trio families (a child and both parents) for genomic and DNA analysis. Records of genetic traits in families (pedigrees) will be analyzed in conjunction with the DNA samples to search for intermediate phenotypes. A whole genome scan will then be used to search for genetic linkage using the intermediate phenotypes, and the two best positional candidate genes will be studied using the established pedigrees and trio families. Project Status


Funder National Institutes of Health
Fiscal Year Funding $448,943.00
Project Number 5R01MH069359-05
Principal Investigator Coon, Hilary
Received ARRA Funding? No
Strategic Plan Question Question 3: What Caused This To Happen And Can This Be Prevented? (Risk Factors)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 3LB. Identify genetic risk factors in at least 50% of people with ASD by 2014. IACC Recommended Budget: $33,900,000 over 6 years.
Federal or Private? Federal
Institution University of Utah
State/Country Utah
Web Link 1 Genetics of autism intermediate phenotypes (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Genetics of autism intermediate phenotypes | $499,256.00 | 2008 | R01MH069359-04