Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

ACE Center: Structural and chemical brain imaging of autism  

This grant provides support for an NIH Autism Center of Excellence (ACE). This study seeks to identify early manifestations of abnormal brain development in autism spectrum disorders (ASD). Twelve-month old infant siblings of children with autism, and comparison non-risk infants, will be studied using magnetic resonance imaging (MRI) and magnetic resonance spectroscopic imaging (MRSI), and relationships between brain measures and clinical course and symptom onset will be examined. A second part of the research will examine children entering adolescence in order to identify brain developmental changes that may be related to onset seizure and behavioral decline during the adolescent period. This study will enable understanding of the relationship between variations in brain development and longer-term clinical outcome, focusing on adolescent seizure onset and cognitive decline. Project Status


Funder National Institutes of Health
Fiscal Year Funding $521,038.00
Project Number 5P50HD055782-03
Principal Investigator Dager, Stephen
Received ARRA Funding? No
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Strategic Plan Objective New! Green dot: Objective has greater than or equal to the recommended funding. 2SE. Launch three studies that target the underlying biological mechanisms of co-occurring conditions with autism including seizures/epilepsy, sleep disorders and familial autoimmune disorders by 2012. IACC Recommended Budget: $9,000,000 over 5 years.
Federal or Private? Federal
Institution University of Washington
State/Country Washington
Web Link 1 ACE Center: Structural and chemical brain imaging of autism (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects ACE Center: Structural and chemical brain imaging of autism | $514,982.00 | 2010 | 5P50HD055782-04