Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Functional neuroimaging of psychopharmacologic intervention for autism  

This is a mentored Research Career Development Award to support the career development of clinical investigators in patient-oriented research. This study seeks to use measures of brain functioning to help understand how an effective intervention reduces symptoms in individuals with autism spectrum disorders. The neural, symptomatic, and neuropsychological profiles of treatment response in autism will be examined concurrently. The project will use functional magnetic resonance imaging (fMRI) to investigate neurobiological links between neurocognitive processes mediating symptom expression and domain-specific symptom reductions induced by citalopram in high-functioning adults with autism. The findings of the study may lead to future research aimed at developing better interventions with the ultimate goal of reducing suffering for individuals with neurodevelopmental disorders. Project Status


Funder National Institutes of Health
Fiscal Year Funding $155,901.00
Project Number 5K23MH081285-02
Principal Investigator Dichter, Gabriel
Received ARRA Funding? No
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Strategic Plan Objective New! Green dot: Objective has greater than or equal to the recommended funding. 2LB. Launch at least three studies which evaluate the applicability of ASD phenotype and/or biological signature findings for performing diagnosis, risk assessment, or clinical intervention by 2015. IACC Recommended Budget: $7,200,000 over 5 years.
Federal or Private? Federal
Institution University of North Carolina at Chapel Hill
State/Country North Carolina
Web Link 1 Functional neuroimaging of psychopharmacologic intervention for autism (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Functional neuroimaging of psychopharmacologic intervention for autism | $158,810.00 | 2010 | 5K23MH081285-03
Functional neuroimaging of psychopharmacologic intervention for autism | $154,492.00 | 2008 | K23MH081285-01A1