This grant provides support for an NIH Autism Center of Excellence (ACE). This ACE focuses on early identification methods and uses a novel variant of functional magnetic resonance imaging (fMRI) activation studies on ASD at age 2-years. The current project will study 12-month old infants at-risk for ASD, infants at-risk for developmental delay, and typical infants using advanced biological and behavioral methods. The overarching objective of the Administrative Core is professional and efficient operations and provision of services related to the overall planning, direction, and internal monitoring and review of ACE activities; organization of the annual Advisory Committee meetings and biweekly meetings of Core and project leaders with the Director; fiduciary oversight of the component Core and project budgets; and management and presentation of the "public face" of the Center in all facets of outreach to and interaction with the academic and scientific community as well as other regional, national, and international stakeholder groups, including dissemination of ACE research and general informational materials. In short, the Core's primary purpose and goal is full and proper accountability.