Project Detail
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Allosteric potentiators of the oxytocin system for the control of social motivation  

Oxytocin is a peptide hormone that affects complex social behaviors in mammals. Deficits in the oxytocin pathway have been implemented in several human diseases and disorders, including schizophrenia and autism, but there remains a severe dearth of chemical probes to interrogate the oxytocin pathway and to develop pharmaceutical agents. This proposal describes a high throughput screen to identify oxytocin receptor agonists and positive allosteric modulators to be used as leads for the design of chemical probes to investigate the oxytocin pathway with particular attention to its role in social behavior. Project Status


Funder National Institutes of Health
Fiscal Year Funding $25,000.00
Project Number 1R03MH085678-01A1
Principal Investigator Jarstfer, Michael
Received ARRA Funding? No
Strategic Plan Question Question 3: What Caused This To Happen And Can This Be Prevented? (Risk Factors)
Strategic Plan Objective 3O. Not specific to Question 3 objectives
Federal or Private? Federal
Institution University of North Carolina at Chapel Hill
State/Country North Carolina
Web Link 1 Allosteric potentiators of the oxytocin system for the control of social motivation (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects N/A