Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

A comparative developmental connectivity study of face processing  

This study will examine the similarities and differences of face processing in the developing brains of humans (children, adolescents, and adults) and non-human primates (NHPs) using functional magnetic resonance imaging (fMRI) to explore the functional neural circuitry involved in face processing. The overall scientific goal is to characterize the large-scale anatomical and functional brain networks in humans and NHPs for the perception of faces and for the processing of emotions in the face. Both capacities are critical for highly social organisms, but species-specific experiences may modulate these networks differently. A better understanding of brain connectivity patterns for face processing in humans and non-human primates can help develop animal models of typical and atypical social development. Such findings can be used to target behavioral or pharmacological interventions for conditions like autism spectrum disorder or Williams syndrome. Project Status


Funder National Institutes of Health
Fiscal Year Funding $267,046.00
Project Number 1R21MH086958-01
Principal Investigator Joseph, Jane
Received ARRA Funding? No
Strategic Plan Question Question 4: Which Treatments And Interventions Will Help? (Interventions)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 4SB. Standardize and validate at least 20 model systems (e.g., cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012. IACC Recommended Budget: $75,000,000 over 5 years.
Federal or Private? Federal
Institution University of Kentucky
State/Country Kentucky
Web Link 1 A comparative developmental connectivity study of face processing (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects A comparative developmental connectivity study of face processing | $296,461.00 | 2010 | 5R21MH086958-02