Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Multimodal brain imaging in autism spectrum disorders  

This is a mentored research scientist development award to support an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Several lines of evidence provide support for a model of abnormal connectivity to explain the underlying neuropathology of autism. In this study, functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) will be used to investigate abnormalities in neural connectivity in ASD. The study will examine two domains of impairment (face perception and response to social information) and determine how neural connectivity relates to symptom severity. Twenty-five individuals with high functioning ASD and 25 typically developing (TD) individuals will participate in the study. Overall, this research will assess the integrity of white matter connections that underlie specific impairments in ASD. Project Status


Funder National Institutes of Health
Fiscal Year Funding $165,397.00
Project Number 5K01NS059675-02
Principal Investigator Kleinhans, Natalia
Received ARRA Funding? No
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Strategic Plan Objective 2O. Not specific to Question 2 objectives
Federal or Private? Federal
Institution University of Washington
State/Country Washington
Web Link 1 Multimodal brain imaging in autism spectrum disorders (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Multimodal brain imaging in autism spectrum disorders | $167,832.00 | 2010 | 5K01NS059675-03
Multimodal brain imaging in autism spectrum disorders | $162,151.00 | 2008 | K01NS059675-01A1