Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Maternal dietary factors and risk of autism spectrum disorders  

Research suggests that autism may result from environmental factors that act during prenatal development. One idea is that a pregnant woman's diet could influence prenatal brain development, perhaps in a way that increases autism risk. Relatively little research has been dedicated to understanding how maternal dietary factors could influence brain development in offspring. One interesting dietary factor is intake of omega-3 fatty acids, which are found in fish and nut oils; these fatty acids may act in the brain to promote neural growth. Dr. Santagelo's fellow will determine whether women with low intakes of omega-3 fatty acids during pregnancy have increased risk of having a child with autism. The women studied will be from The Nurses' Health Study II cohort, a large cohort of over 100,000 female United States nurses who have been followed prospectively since 1989. The information collected on this group includes medical, obstetrical, and prospectively collected dietary factors, including omega-3 fatty acid intake. In 2005, over 800 women in the cohort reported having had a child with an autism diagnosis. This study will compare omega-3 fatty acid intakes in women with children with autism to the intake of women without children with autism in order to characterize the relationship between maternal diet and risk of autism. Project Status


Funder Autism Speaks
Fiscal Year Funding $32,000.00
Project Number 2210
Principal Investigator Santangelo, Susan
Received ARRA Funding? No
Strategic Plan Question Question 3: What Caused This To Happen And Can This Be Prevented? (Risk Factors)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 3LD. Support ancillary studies within one or more large-scale, population-based surveillance and epidemiological studies, including U.S. populations, to collect data on environmental factors during preconception, and during prenatal and early postnatal development, as well as genetic data, that could be pooled (as needed), to analyze targets for potential gene/environment interactions by 2015. IACC Recommended Budget: $44,400,000 over 5 years.
Federal or Private? Private
Institution Harvard Medical School
State/Country Massachusetts
Web Link 1 Maternal dietary factors and risk of autism spectrum disorders (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Maternal dietary factors and risk of autism spectrum disorders | $0.00 | 2010 | 2210