Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Cerebral asymmetry and language in autism  

Preliminary evidence suggests that there is a reduction in the volume of the brain region planum temporale in both adults and children with autism. The planum temporale (PT) is an auditory processing brain region intimately associated with language processing in the left hemisphere in normal development. Using magnetic resonance imaging (MRI), the researchers will measure the volume of the left hemisphere PT in 20 parents of children with autism, 20 age-matched adults with autism, and 20 adults with no personal or familial history of autism. Language function and family history of language development will also be assessed in the same three groups of adults and correlated to the MRI findings. The researchers hypothesize that reduction in PT volume will be present in the parents of children with autism. Such a finding would bolster the hypothesis that PT volume reduction represents a familial risk factor for language delay in autism. Project Status


Funder National Institutes of Health
Fiscal Year Funding $6,798.00
Project Number 5P41RR013642-12
Principal Investigator Rojas, Donald
Received ARRA Funding? No
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Strategic Plan Objective New! Green dot: Objective has greater than or equal to the recommended funding. 2LB. Launch at least three studies which evaluate the applicability of ASD phenotype and/or biological signature findings for performing diagnosis, risk assessment, or clinical intervention by 2015. IACC Recommended Budget: $7,200,000 over 5 years.
Federal or Private? Federal
Institution University of California, Los Angeles
State/Country California
Web Link 1 Cerebral asymmetry and language in autism (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Cerebral asymmetry and language in autism | $2,576.00 | 2008 | P41RR013642-11