Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

An open resource for autism iPSCs and their derivatives  

The overall purpose of this project is to overcome a critical barrier in the field of autism research; namely, accessibility to statistically relevant numbers of patient-derived neural tissues. This novel strategy, which is based on considerable human neural stem cell (NSC), human embryonic stem cell (ESC), and biorepository experience, is to obtain fibroblasts from specific autism and control patients, derive induced pluripotent stem cells (iPSCs) from the fibroblasts, differentiate NSCs from the iPSCs, characterize and contrast and compare these cells using gene microarray and bioinformatics techniques, and provide the cells to specific autism researchers. Project Status


Funder National Institutes of Health
Fiscal Year Funding $617,911.00
Project Number 1R01HD059967-01A2
Principal Investigator Schwartz, Philip
Received ARRA Funding? No
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 2SC. Identify ways to increase awareness among the autism spectrum community of the potential value of brain and tissue donation to further basic research by 2011. IACC Recommended Budget: $1,400,000 over 2 years.
Federal or Private? Federal
Institution Children's Hospital of Orange County
State/Country California
Web Link 1 An open resource for autism iPSCs and their derivatives (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects An open resource for autism iPSCs and their derivatives | $561,413.00 | 2010 | 5R01HD059967-02