Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

A study of autism  

The Simons Simplex Collection, a repository of data on 2,000 families affected by autism, is a rich source of information for epidemiologic studies. However, because the data are collected at numerous institutions using a variety of methods, detecting meaningful trends across the entire collection will require serious statistical firepower. Abba Krieger and his colleagues plan to undertake this task. The data (collected from children with autism, their parents, and unaffected siblings) include demographics, medical histories of the affected children and their families, and results of various social and intelligence tests. Krieger has assembled a team of statisticians, mathematicians, bioinformatics experts and other researchers to review the data for accuracy, standardize it, and organize it into forms that are useful for statistical analyses. The researchers propose to comb the data for relationships between autism and demographic and environmental variables, and explore associations between data from the affected children and their family members. The researchers also plan to look for 'clusters' of individuals with similar data, which might provide insight into the variety of disorders that make up the autism spectrum. Project Status


Funder Simons Foundation
Fiscal Year Funding $108,701.00
Project Number 121221
Principal Investigator Krieger, Abba
Received ARRA Funding? No
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Strategic Plan Objective New! Green dot: Objective has greater than or equal to the recommended funding. 2LB. Launch at least three studies which evaluate the applicability of ASD phenotype and/or biological signature findings for performing diagnosis, risk assessment, or clinical intervention by 2015. IACC Recommended Budget: $7,200,000 over 5 years.
Federal or Private? Private
Institution University of Pennsylvania
State/Country Pennsylvania
Web Link 1 A study of autism (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects A study of autism | $291,461.00 | 2010 | 121221
A study of autism | $217,402.00 | 2008 | Project number unavailable
A study of autism | $162,232.00 | 2011 | 121221
A study of autism | $162,232.00 | 2012 | 121221