Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

CNTNAP2 in a behavioral model of autism  

Children diagnosed with autism fail to develop language, have other social difficulties, and overly repetitive behaviors. To understand the neural basis for these deficits, the researchers will develop a novel model of autism using songbirds, arguably the only practical laboratory model for probing the vocal learning subcomponent of language. Researchers will investigate the role of the autism susceptibility gene, Cntnap2, on vocal learning and other social and repetitive behaviors, with the goal of applying these findings to humans and formulating novel approaches to improve social interactions, speech learning, and the quality of life of autistic children. Project Status


Funder National Institutes of Health
Fiscal Year Funding $265,450.00
Project Number 1R21HD065271-01
Principal Investigator White, Stephanie
Received ARRA Funding? Yes
Strategic Plan Question Question 4: Which Treatments And Interventions Will Help? (Interventions)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 4SB. Standardize and validate at least 20 model systems (e.g., cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012. IACC Recommended Budget: $75,000,000 over 5 years.
Federal or Private? Federal
Institution University of California, Los Angeles
State/Country California
Web Link 1 CNTNAP2 in a behavioral model of autism (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Cntnap2 in a behavioral model of autism | $262,356.00 | 2010 | 5R21HD065271-02