Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

White matter connections of the face processing network in children and adults  

This is an individual National Research Service Award for pre-doctoral research training, which provides support for promising doctoral candidates who will be performing dissertation research and training in a scientific health-related field. Faces are a rich source of information, offering a window to identity, ethnicity, age, gender, and changing mental and emotional states. Recognizing this facial information is critical for social interaction and is atypical in developmental disorders of social communication, such as autism and Williams syndrome. The processing involved in decoding facial information is thought to depend on a network of core perceptual face processing regions in the brain that undergo prolonged maturation well into adolescence. However, little is known about the pattern of neural (primarily axonal) connectivity of the core face processing network or about the typical developmental timecourse of these connections. This study will use neuroimaging methods to characterize these connections in the typically-developing brain from 7 years of age through adulthood. In the same subjects, behavioral measurements of face recognition (identity, expression) will also be collected to enable comparison of quantitative measures of white matter connections between face processing regions and face recognition performance at the behavioral level. By charting the typical developmental timecourse of white matter connections, this research will aid understanding of how the structural organization of the face processing network is disturbed in developmental disorders of social information processing. Understanding the timecourse of typical development of this network may help to identify time windows and targets for treatment interventions. Project Status


Funder National Institutes of Health
Fiscal Year Funding $41,176.00
Project Number 1F31MH088232-01
Principal Investigator Yoon, Jennifer
Received ARRA Funding? No
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Strategic Plan Objective New! Yellow dot: Objective has some degree of funding, but less than the recommended amount. 2SD. Launch three studies that target improved understanding of the underlying biological pathways of genetic conditions related to autism (e.g. Fragile X, Rett syndrome, tuberous sclerosis complex) and how these conditions inform risk assessment and individualized intervention by 2012. IACC Recommended Budget: $9,000,000 over 5 years.
Federal or Private? Federal
Institution Stanford University
State/Country California
Web Link 1 White matter connections of the face processing network in children and adults (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects N/A