Autism is increasingly understood as a disconnection syndrome, where an under-connectivity between certain brain regions could underlie social and cognitive deficits. The researchers will apply a novel brain imaging approach to better understand the brain mechanisms and interconnectedness of brain regions involved in autism. Using resting state blood-oxygenation level-dependent functional magnetic resonance imaging (fMRI), the researchers will image two brain networks that in neurotypical controls are commonly associated with social and cognitive control skills, both of which are thought to be disrupted in individuals with autism. Thirty adult males with high-functioning autism will be compared their to 30 matched neurotypical volunteers. Measures of functional connectivity will be correlated with performance on behavioral tasks using the Social Responsiveness Scale and the Behavioral Response Inventory of Executive Functions. The proposed work introduces new techniques for the study of brain circuits in autism and has the potential to further inform the understanding of the neural basis of autism so that improved methods of diagnosis and treatment can be developed.