Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Identifying brain-based biomarkers for ASD & their biological subtypes  

The ultimate goal of this research program is to identify brain biomarkers of autism spectrum disorders (ASDs) and biologically-based ASD subtypes using multimodal magnetic resonance imaging (MRI). Participants (children and adults with ASD and healthy controls) undergo high-resolution anatomical MRI, functional MRI (fMRI), diffusion tensor imaging (DTI), and magnetic resonance spectroscopy (MRS). These diverse forms of data will be analyzed within a single imaging space using advanced image acquisition, image processing, and statistical modeling. These methods will facilitate a deeper understanding of the relationships between local volumes, functional activity, metabolite concentrations, and connectivity. Neurobiological ASD subtypes may emerge based on differential patterns of disturbances in distinct neural systems, and the identification of brain-based biomarkers in individuals with ASD will illuminate the neural bases of this heterogeneous disorder. Project Status


Funder National Institutes of Health
Fiscal Year Funding $1,224,886.00
Current Award Period 2009-2011
Project Number 5R01MH089582-02
Principal Investigator Peterson, Bradley
Received ARRA Funding? Yes
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Subcategory Subgroups/Biosignatures
Strategic Plan Objective 2O. Not specific to Question 2 objectives
Federal or Private? Federal
Institution New York State Psychiatric Institute
State/Country New York
Web Link 1 Identifying brain-based biomarkers for ASD & their biological subtypes (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Identifying brain-based biomarkers for ASD & their biological subtypes | $1,206,925.00 | 2009 | 1R01MH089582-01