Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Regulation of activity-dependent ProSAP2 synaptic dynamics  

This is an individual National Research Service Award for pre-doctoral research training, which provides support for a promising doctoral candidate to perform dissertation research and training in a scientific health-related field. Autism is a prevalent developmental disorder, characterized by deficits in social interaction and communication. Though twin studies suggest a strong genetic component, genetic mapping studies have failed to identify a single gene underling this complex social disorder. Rather, they have implicated several interacting synaptic proteins that are involved in cell adhesion and cytoskeletal architecture, including the protein ProSAP2. Using cultured cells, this project explores the synaptic mechanisms regulating the dynamics of ProSAP2, a particulariy interesting protein implicated in autism spectrum disorders. Project Status


Funder National Institutes of Health
Fiscal Year Funding $41,380.00
Current Award Period 2009-2012
Project Number 5F31NS066786-02
Principal Investigator Rowan, Magali
Received ARRA Funding? No
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Subcategory Molecular Pathways
Strategic Plan Objective 2O. Not specific to Question 2 objectives
Federal or Private? Federal
Institution Stanford University
State/Country California
Web Link 1 Regulation of activity-dependent ProSAP2 synaptic dynamics (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Regulation of activity-dependent ProSAP2 synaptic dynamics | $41,176.00 | 2009 | 1F31NS066786-01