Researchers will study the neural basis of behavior switching and stability, two processes that are disrupted in childhood autism and Parkinson's disease as evidenced by inappropriate initiation and repetition of movements. Motor behavior is determined not only by external stimuli but also by internal states of brain networks that function as sensory motor-integrators. An important type of network state is an experience-dependent state that relies on the memory of recent experiences. Consequently, to generate responses, networks integrate both current stimuli and memories of recent experiences that are expressed as network states. In this study, investigators will define how experience-dependent states are generated, expressed, and integrated with sensory stimuli in the brain using a multidisciplinary approach that combines electrophysiological, biochemical and cell-biological techniques. These studies may lead to novel insights into the nature of the behavioral deficits in these diseases, such as autism and Parkinson's disease.