Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Finding recessive genes for autism spectrum disorders  

The high heritability of autism underscores the fact that autism has a strong genetic component. Historically, our understanding of other diseases with high heritability has benefited greatly from the study of patients for whom these illnesses run in the family. Analysis of these familial cases led to the identification of genes for Cystic Fibrosis and Huntington's, which has in turn led to critical advances in our understanding of disease mechanism, improved diagnosis, and experimental therapies. The goal of this study is to identify special cases of familial autism, in which affected individuals are born to parents with a history of shared ancestry, and to use these cases to discover new autism genes. Project Status


Funder Simons Foundation
Fiscal Year Funding $186,824.50
Current Award Period 2010-2013
Project Number 178093
Principal Investigator Walsh, Christopher
Received ARRA Funding? No
Strategic Plan Question Question 3: What Caused This To Happen And Can This Be Prevented? (Causes)
Subcategory Genetic Risk Factors
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 3LB. Identify genetic risk factors in at least 50% of people with ASD by 2014. IACC Recommended Budget: $33,900,000 over 6 years.
Federal or Private? Private
Institution Children's Hospital Boston
State/Country Massachusetts
Web Link 1 Finding recessive genes for autism spectrum disorders (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Finding recessive genes for autism spectrum disorders | $361,824.00 | 2011 | 178093
Finding recessive genes for autism spectrum disorders | $349,999.00 | 2012 | 178093