Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Assisted reproductive treatments and risk of autism  

In the past decade, the use of assisted reproductive treatments such as in vitro fertilization and intracytoplasmatic sperm injection has consistently increased, with approximately 1% of infants born in 2004 being conceived through such treatments. As well, there is accumulating evidence suggesting that there may be a relationship between the use of assisted reproductive treatments and autism spectrum disorders (ASD) in children born as the result of such treatments. In the present study, researchers will use population-based health records collected in Sweden for all infants born between 1982 and 2001, including those born after assisted reproduction treatments. Dr. Reichenberg and colleagues will analyze the data to determine whether diagnoses of ASD link to the use of assisted reproductive treatments as well as to other potentially relevant factors such as parental age and perinatal indices such as birth weight. Project Status


Funder Autism Speaks
Fiscal Year Funding $59,686.00
Current Award Period 2009-2010
Project Number 3681
Principal Investigator Reichenberg, Avi
Received ARRA Funding? No
Strategic Plan Question Question 3: What Caused This To Happen And Can This Be Prevented? (Causes)
Subcategory Environment
Strategic Plan Objective New! Yellow dot: Objective has some degree of funding, but less than the recommended amount. 3SH. Support at least three studies of special populations or use existing databases to inform our understanding of environmental risk factors for ASD in pregnancy and the early postnatal period by 2012. Such studies could include: o Comparisons of populations differing in geography, gender, ethnic background, exposure history (e.g., prematurity, maternal infection, nutritional deficiencies, toxins), and migration patterns; and o Comparisons of phenotype (e.g., cytokine profiles), in children with and without a history of autistic regression, adverse events following immunization (such as fever and seizures), and mitochondrial impairment. These studies may also include comparisons of phenotype between children with regressive ASD and their siblings. oEmphasis on environmental factors that influence prenatal and early postnatal development is particularly of high priority. Epidemiological studies should pay special attention to include racially and ethnically diverse populations. IACC Recommended Budget: $12,000,000 over 5 years.
Federal or Private? Private
Institution Institute of Psychiatry, King's College London
State/Country United Kingdom
Web Link 1 Assisted reproductive treatments and risk of autism (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Assisted reproductive treatments and risk of autism | $60,000.00 | 2009 | 3681
Assisted reproductive treatments and risk of autism | $20,000.00 | 2008 | 3681
Assisted reproductive treatments and risk of autism | $0.00 | 2011 | 3681