Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Neurogenomics in a model for procedural learning  

This is an individual National Research Service Award for pre-doctoral research training, which provides support for promising doctoral candidates who will be performing dissertation research and training in a scientific health-related field. FoxP2 is currently the only molecule directly linked to a developmental-onset human speech and language disorder and has been implicated as a susceptibility gene for ASD. The fellow will study songbirds to further characterize the role of FoxP2 in vocal communication. Similarities between human speech and birdsong make songbirds a unique model system to test molecules involved in language and social communication using molecular, physiological, and behavioral analyses. By understanding how the normal and mutated forms of these genes and their gene targets operate in animal models like the songbird, this research will contribute to the understanding of neural mechanisms underlying human speech and associated autism spectrum disorders. Results from this study may facilitate the development of therapeutic interventions to treat language and cognitive deficits in ASD and related communication disorders. Project Status
ONGOING

2010

Funder National Institutes of Health
Fiscal Year Funding $33,053.00
Current Award Period 2008-2011
Project Number 5F31MH082533-03
Principal Investigator Hilliard, Austin
Received ARRA Funding? No
Strategic Plan Question Question 4: Which Treatments And Interventions Will Help? (Treatments)
Subcategory Model Systems/Therapeutic Targets
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 4SB. Standardize and validate at least 20 model systems (e.g., cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012. IACC Recommended Budget: $75,000,000 over 5 years.
Federal or Private? Federal
Institution University of California, Los Angeles
State/Country California
Web Link 1 Neurogenomics in a model for procedural learning (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Neurogenomics in a model for procedural learning | $31,848.00 | 2009 | 5F31MH082533-02
Neurogenomics in a model for procedural learning | $30,774.00 | 2008 | F31MH082533-01A1