Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Regulation of gene expression in the brain  

Behavioral studies using a mouse model lacking the vasopressin 1b receptor (Avp1b) and oxytocin receptor (oxtr) (conditional knock-out mouse) may provide new information in understanding mental health issues in humans. Project Status


Funder National Institutes of Health
Fiscal Year Funding $2,086,763.00
Current Award Period Ongoing
Project Number 1ZIAMH002498-21
Principal Investigator Young, Walter
Received ARRA Funding? No
Strategic Plan Question Question 4: Which Treatments And Interventions Will Help? (Treatments)
Subcategory Model Systems/Therapeutic Targets
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 4SB. Standardize and validate at least 20 model systems (e.g., cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012. IACC Recommended Budget: $75,000,000 over 5 years.
Federal or Private? Federal
Institution National Institutes of Health
State/Country Maryland
Web Link 1 Regulation of gene expression in the brain (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Regulation of gene expression in the brain | $2,125,882.00 | 2009 | 1ZIAMH002498-20
Regulation of gene expression in the brain | $1,548,920.00 | 2008 | Z01MH002498-19