Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Early detection and intervention in infants at risk for autism  

According to the University of Wisconsin Autism Center of Excellence model, early autism risk factors (genetic/familial and environmental) lead to risk processes, namely altered patterns of interaction between the child and his/her environment, which contribute to the abnormal development of neural circuitry and atypical behaviors. The goals of this project are two-fold: First, in a sample of infant sibs, the aim is to investigate whether neurophysiological risk indices (endophenotypes) measured at 6-7 mos of age will improve our ability to identify infants who will develop autism or autism-related symptoms by age 2. Second, researchers will assess whether it is possible to alter risk processes via early intervention with high-risk infants, thereby reducing severity of autism symptoms.


Funder National Institutes of Health
Fiscal Year Funding $627,746.00
Project Number P50HD055782-02
Principal Investigator Dawson, Geraldine
Strategic Plan Question Question 1: When Should I Be Concerned? (Diagnosis)
Strategic Plan Objective Yellow dot: Objective has some degree of funding, but less than the recommended amount. 1.4 Develop at least five measures of behavioral and/or biological heterogeneity in children or adults with ASD, beyond variation in intellectual disability, that clearly relate to etiology and risk, treatment response and/or outcome by 2015. IACC Recommended Budget: $71,100,000 over 5 years.
Federal or Private? Federal
Institution University of Washington
State/Country Washington
Web Link 1 No URL available.
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects ACE Center: Early detection and intervention in infants at risk for autism | $620,446.00 | 2010 | 5P50HD055782-04
ACE Center: Early detection and intervention in infants at risk for autism | $627,746.00 | 2009 | 5P50HD055782-03