Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Neuroimmunologic investigations of autism spectrum disorders (ASD)  

The clinical course suggests that there may be a unique alteration in immune function among children with regressive autism. Researchers are evaluating this hypothesis through a combination of phenotyping investigations and treatment trials. The current phenotyping investigation is evaluating children with regressive autism and expects to find that at least some children have demonstrable abnormalities in immune function. The specific aims of the study are to characterize the immune response in children with autism and to identify neurobiologic markers for autism through the techniques of metabolomics, proteomics and genomics.


Funder National Institutes of Health
Fiscal Year Funding $512,425.00
Project Number Z01MH002915-01
Principal Investigator Swedo, Susan
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 2.2 Support at least four research projects to identify mechanisms of metabolic and/or immune system interactions with the central nervous system that may underlie the development of ASD during prenatal-postnatal life by 2010. IACC Recommended Budget: $9,800,000 over 4 years.
Federal or Private? Federal
Institution National Institutes of Health
State/Country Maryland
Web Link 1 No URL available.
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Neuroimmunologic investigations of autism spectrum disorders (ASD) | $385,337.00 | 2010 | 1ZIAMH002915-03
Neuroimmunologic investigations of autism spectrum disorders (ASD) | $348,146.00 | 2009 | 1ZIAMH002915-02